Myelofibrosis presenting as spinal cord compression.
نویسندگان
چکیده
This report describes a case of myelofibrosis presenting as spinal cord compression on account of extramedullary haemopoietic tissue encroaching upon the spinal cord from a large pelvic mass.
منابع مشابه
Chronic Idiopathic Myelofibrosis Presenting as Cauda Equina Compression due to Extramedullary Hematopoiesis: A Case Report
Extramedullary hematopoiesis (EMH) is occasionally reported in idiopathic myelofibrosis and is generally found in the liver, spleen, and lymph nodes several years after diagnosis. Myelofibrosis presenting as spinal cord compression, resulting from EMH tissue is very rare. A 39-yr-old man presented with back pain, subjective weakness and numbness in both legs. Sagittal magnetic resonance imaging...
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BACKGROUND In Primary Myelofibrosis (PMF; a clonal disorder arising from the neoplastic transformation of early hematopoietic stem cells) patients, spinal cord compression (SCC) is a common complication or even a presentation symptom due to extramedullary hematopoiesis (EMH). However, a case of SCC caused by a spinal abscess is unusual. To the best of our knowledge, this is the first case repor...
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A 50-year-old man with a 20-year history of myelofibrosis developed mild impairment of dorsal column sensation and ataxia of gait. A myelogram and subsequent peroperative biopsy demonstrated spinal cord compression due to extramedullary haematopoiesis. There was an excellent clinical response to surgery and radiotherapy. The characteristic clinical features and the pathogenesis of this unusual ...
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References APPLEBY, A., BATSON, G.A., LASSMAN, L.P. & SIMPSON, C.A. (1964) Spinal cord compression by extramedullary haematopoiesis in myelosclerosis. J. Neurol. Neurosurg. Psychiat. 27, 313. ASK-UPMARK, E. (1945) Tumour-simulating intra-thoracic heterotopia of bone marrow, Acta radiol. (Stockh.), 26, 425. BRANNAN, D. (1927) Extramedullary hematopoiesis in anaemias. Bull. Johns Hopk. Hosp. 41 1...
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ورودعنوان ژورنال:
- Journal of clinical pathology
دوره 56 2 شماره
صفحات -
تاریخ انتشار 2003